Synchronization error between the OST and related Exchange mailbox. Multiple users access the same OST file in one time.
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Causes behind Outlook OST cannot be Accessed Error
This simple and initial method may be helpful to fix cannot accessed error.
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Close all the Outlook Processes
This method may fix your issue. In this you need to disable the cache Exchange Mode.
Disable Cached Exchange Mode
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Disable Outlook Add-ins
Add-ins are used to enhance the performance of the tool or any application. But sometimes, it can be the possible ground for technical error in Outlook application.
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Run Scan OST.Exe Application
This is the last but potent method to fix “Outlook OST cannot be accessed error”. As this is the inbuilt tool provided by Microsoft.
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Repair OST file using OST Recovery Tool
The OST file repair tool competently recuperates corrupt OST file and repairs it without taking too much time.